What is Liraglutide?

Liraglutide the active substance in Saxenda which is a self-injected prefilled pen used once daily that can help adults with a BMI greater than or equal to 30 to lose weight and keep it off.

It helps aid adults with excess weight (BMI ≥28) who also have weight-related medical problems or those with  obesity (BMI ≥30) to lose weight and keep the weight off.

Liraglutide (Saxenda) is not for the treatment of type 2 diabetes and should not be used with any other GLP-1 receptor agonist used in the treatment of Type 2 diabetes eg Victoza, Byetta, Bydureon, Lixumia, Trulicity or Ozempic).

If you are diabetic then we will only supply Liraglutide (Saxenda) if your diabetes is controlled by diet alone and you are not on any medication for it. 

This is because it will affect your diabetes control and adjustments to your usual medicines may be needed.

How does Liraglutide (Saxenda) work?

Saxenda contains the active ingredient Liraglutide.

GLP-1 is a hormone that is released within the body in response to food intake and acts as a physiological regulator of appetite.

Liraglutide, the active substance in Saxenda, is 97% similar to GLP-1 and works in the brain to decrease appetite and thereby reduce food intake resulting in weight loss.

Liraglutide (Saxenda) should be used alongside a reduced-calorie diet and increased physical activity for chronic weight management in adult patients with an initial body mass index, BMI of 30 (obese) or 27 or greater (overweight) in the presence of at least one other chronic health condition (eg, high blood pressure, diabetes, or high cholesterol).

Once your BMI has reached 27 our doctor will no longer be able to prescribe it for you. Hopefully, the healthy habits that you have acquired on your weight loss journey will enable you to get to a BMI where you are no longer overweight (BMI 18.5-24.9).

You should only continue using Liraglutide (Saxenda) if you have lost at least 5% of your initial body weight after 12 weeks on the 3 mg/day dose

How do I use Saxenda?

Please read the patient information leaflet here before using and watch the video.

Liraglutide (Saxenda) is administered once daily.

Inject your dose of Liraglutide (Saxenda) under the skin (subcutaneous injection) in your stomach area (abdomen), upper leg (thigh), or upper arm. It is also recommended that you alternate the site at which the injection is made.

Do not inject into a vein or muscle.

Push the needle all the way into the skin at a 90º angle.

Inject the Saxenda by pushing the button at the top of the pen and leave the syringe in place while you count slowly to 6 to make sure the full dose is delivered.

If the disposable needle found at the tip of one of your Saxenda pens bends out of shape whilst you are trying to use the pen, you should discard the needle and use a new one.

Never share your Saxenda pen or needles with another person. You may give an infection to them, or get an infection from them.

What does the Liraglutide (Saxenda) pen look like?

You can order an individual pen, 2, 3, 4 or 5 pens at once.

You use a gradually increasing dose over the first 5 weeks.

If you are just starting to use Saxenda then a single pen should last 17 days and a pack of 5 pens should last 44 days.

Once you are on the full dose, a pack of 5 pens should last 30 days

How much Liraglutide (Saxenda) do I need?

You should follow a 5-week dose escalation to reach the fully effective 3-mg dose. The 5-week dose-escalation period can reduce the likelihood of gastrointestinal symptoms.

The Saxenda starting dose is 0.6 mg subcutaneously, SC, per day for 1 week.

You should increase the dose by 0.6 mg each week until the full maintenance dose of 3 mg is reached.

By the start of the fifth week you should be on the maximum maintenance dose.

• Week 1 - 0.6 mg SC once daily x 7 days
• Week 2 - 1.2 mg SC once daily x 7 days
• Week 3 - 1.8 mg SC once daily x 7 days
• Week 4 - 2.4 mg SC once daily x 7 days
• Week 5 onwards ı 3.0 mg SC once daily 

You should have lost at least 5% of your starting body weight by week 12 if you want to continue with Liraglutide (Saxenda).

When do I take Liraglutide (Saxenda)?

Saxenda can be taken at any time of the day, with or without food and drink, but you must stick to taking it at the same time each day such as at breakfast or bedtime. Choose a time of the day that works best for you.

What if I forget to take a dose of Liraglutide (Saxenda)?

If you forget to take a dose, but remember within 12 hours of when you would usually take it, take the missed dose as soon as you remember.

If more than 12 hours have passed since you would usually take it, skip the dose and continue like normal the next day.

Do not take a double dose or increase the dose the following day to make up for the missed dose.

If you use more Saxenda than you should, talk to your doctor or go to a hospital straight away. Take the medicine pack with you. You may need medical treatment.

The following effects may happen: • feeling sick (nausea) • being sick (vomiting).

Do I store it in a fridge?

Saxenda needs to be stored in a fridge and so it will be delivered in temperature controlled packaging. The packaging has a limited life span and therefore, if you select having it delivered to a pickup shop then you must collect it on the day that it’s delivered there and refrigerate it as soon as possible.

Also, because Saxenda is temperature sensitive, if you order after 4pm on Thursday it will be sent out on Monday for free tracked delivery on Tuesday. You can upgrade to a Saturday delivery for only £4.

Liraglutide (Saxenda) Storage and Expiry

Do not use Saxenda after the expiry date which is stated on the pen label and carton after ‘EXP’. The expiry date refers to the last day of that month.

Before first use: Store in a refrigerator (2°C to 8°C). Do not freeze. Keep away from the freezer compartment.

Once you start using the pen: You can keep the pen for 1 month when stored at a temperature below 30°C or in a refrigerator (2°C to 8°C). When you are not using the pen, keep the pen cap on in order to protect it from light. Do not use this medicine if the solution is not clear and colourless or almost colourless.

What needles do I use?

The Saxenda pens can be used with NovoFine ;32G Tip, one of the thinnest and shortest needles available from Novo Nordisk. NovoFine 32G

Tip needles are single-use, disposable injection needles.

We will supply the Saxenda pen with the needles and a yellow sharps box to dispose of used needles. 

When the sharps bin is full, it should be returned to your nearest local Household Waste Recycling Centre where it will be disposed of properly.

Only fill the bin up to where it says "Do not fill above this line". You can find your local council here www.gov.uk/find-local-council

You must not put used needles or other sharps in any of your household waste bins.

Are there any side-effects?

Like all medicines, this medicine can cause side effects, although not everybody gets them.

Serious side-effects

• Some severe allergic reactions (anaphylaxis) have been reported rarely in patients using Saxenda. You should see your doctor straight away if you get symptoms such as breathing problems, swelling of face and throat and a fast heartbeat.

• Cases of inflammation of the pancreas (pancreatitis) have been reported uncommonly in patients using Saxenda. Pancreatitis is a serious, potentially life-threatening medical condition. Stop taking Saxenda and contact a doctor immediately if you notice any of the following serious side effects:-
• Severe and persistent pain in the abdomen (stomach area) which might reach through to your back, as well as nausea and vomiting, as it could be a sign of an inflamed pancreas (pancreatitis).

Other side effects :-

Very common: may affect more than 1 in 10 people

• Feeling sick (nausea), being sick (vomiting), diarrhoea, constipation – these usually go away after a few days or weeks.

Common: may affect up to 1 in 10 people

• Problems affecting the stomach and intestines, such as indigestion (dyspepsia), inflammation in the lining of the stomach (gastritis), stomach discomfort, upper stomach pain, heartburn, feeling bloated, wind (flatulence), belching and dry mouth Feeling weak or tired Changed sense of taste Dizziness Difficulty sleeping (insomnia). This usually occurs the first 3 months of treatment Gallstones Injection site reactions (such as bruising, pain, irritation, itching and rash) Low blood sugar (hypoglycaemia).

The warning signs of low blood sugar may come on suddenly and can include: cold sweat, cool pale skin, headache, fast heartbeat, feeling sick, feeling very hungry, changes in vision, feeling sleepy, feeling weak, being nervous, being anxious, confusion, difficulty concentrating and shaking (tremor).

Your doctor will tell you how to treat low blood sugar and what to do if you notice these warning signs increase of pancreatic enzymes, such as lipase and amylase which may lead to pancreatitis Uncommon: may affect up to 1 in 100 people

• Loss of fluids (dehydration). This is more likely to occur at the start of treatment and may be due to being sick (vomiting), feeling sick (nausea) and diarrhoea
• Inflamed gall bladder • Allergic reactions including skin rash • Feeling generally unwell
• Faster pulse Rare: may affect up to 1 in 1,000 people Reduced kidney function Acute kidney failure. Signs may include reduction in urine volume, metallic taste in mouth and easily bruising

Any tips for managing nausea?

The most common side effect that you may experience when you first start Saxenda is nausea.

This usually improves as your body adjusts to treatment.

If you do experience nausea, there are some general recommendations that you can follow :-

1. Eat bland, low-fat foods, like crackers, toast, and rice

2. Eat foods that contain water, like soups and gelatin

3. Avoid lying down after you eat

4. Go outside to get some fresh air

If you experience sickness (vomiting) or diarrhoea  it is important to avoid dehydration by drinking plenty of fluids.

Are there any contra-indications?

As there is limited therapeutic experience in patients 75 years of age or over, use in these patients is not recommended

Anyone with liver or kidney disease should not take Saxenda

Hypersensitivity to liraglutide or to any of the excipients listed in the patient information leaflet.

This medicine is not recommended if you have a severe stomach or gut problem which results in delayed stomach emptying (called gastroparesis), or if you have an inflammatory bowel disease.

Liraglutide should be used with caution in patients with thyroid disease.

Upon initiation of liraglutide treatment in patients on warfarin or other coumarin derivatives more frequent monitoring of International Normalised Ratio (INR) is recommended.

Severe heart failure

Disease of the pancreas.

Do not use Saxenda if you are pregnant, think that you might be pregnant or are planning to have a baby. This is because it is not known if Saxenda may affect the baby. Do not breast-feed if you are using Saxenda. This is because it is not known if Saxenda passes into breast milk.

Special warnings and precautions for use

In patients with diabetes mellitus Saxenda must not be used as a substitute for insulin.

Saxenda should not be mixed with other injectables (e.g. insulins).

For successful weight loss help and advice

See the NHS web site

www.nhs.uk/live-well/healthy-weight/start-the-nhs-weight-loss-plan

Would you like to know the truth about

Discover the latest scientific advancements on obesity and its causes and how the many common myths about weight can be disproved by going here:
www.truthaboutweight.global/gb/en.html

Download the patient information leaflet

Patient Information Leaflet for Saxenda

Can I buy Saxenda without a prescription?

No, Saxenda is a prescription-only medication and requires a simple, discreet consultation.

In order to buy Saxenda weight loss pens from Webmed Pharmacy you will either need to provide your own doctors prescription or complete an online consultation with us to ensure this medication is suitable for you.

If you want to know more about Saxenda and if it could work for you then call our pharmacy team 0161 491 1899. Your conversation will be in confidence and with discretion.

Buy Liraglutide (Saxenda)

The Saxenda UK Weight Loss Pen

The Saxenda weight loss pen looks like a pen when closed but is a prefilled self injection and used once daily.

The Saxenda weight loss pen contains the active substance Liraglutide and helps aid adults with excess weight (BMI ≥27) who also have weight-related medical problems or those with  obesity (BMI ≥30)  to lose weight and keep the weight off.

You can order an individual Saxenda pen, or between 2 and 5 pens at once.

You use the Saxenda weight loss pen daily, as a gradually increasing dose over the first 5 weeks.

If you are just starting to use Saxenda then a single pen should last 17 days and a pack of 5 pens should last 44 days.

Once you are on the full dose, a pack of 5 pens should last 30 days

See our Excellent Saxenda UK Reviews

WebMed Pharmacy have many excellent reviews on Saxenda.

WebMed is a online Pharmacy that specialises in treatments where patients may feel embarrassed or awkward talking to their GP, simply find it difficult to get an appointment or don't want to take time off work.

You can complete a simple online medical questionnaire in the comfort of your own home and if suitable can be prescribed Saxenda UK by one of our own Doctors.

See the reviews of our services. We offer a confidential, discreet next working day delivery of medicines, for sensitive or intimate conditions, within a 1 hour time slot to most postcodes in the UK.

We provide treatments for weight loss along with many other prescription medications.

Solve your problem without having to go to your GP and have your medicine prescribed by a GMC  regulated Doctor

WebMed Pharmacy is owned by WebMed Pharmacy Ltd.

Weight loss injections?

The weight loss injections from Saxenda, are in a Pen injection form that is best injected into the stomach area. You attach a Saxenda Pen Needle before dialling up the dose on the Pen and the dial allows you to control the amount of Saxenda you need.

Saxenda Weight Loss Injections are injected under the skin (subcutaneously). You have the choice of injecting your stomach area (abdomen), upper leg (thigh) or upper arm, as instructed by Webmed Pharmacy.

Do not inject into a vein or muscle.

Saxenda injections for weight loss should be used with a reduced-calorie meal plan and increased physical activity.

Saxenda weight loss injections are taken over a 5 week period with an escalating dosage schedule, to reach the maximum therapeutic dosage to help you achieve your maximum weight loss. You then continue on the program until you reach your goal weight with a healthy BMI.

Saxenda weight loss injections, mimics one of your body's natural responses to control your appetite.

Your body naturally produces an appetite hormone known as glucagon-like-peptide (GLP-1) that helps to regulate your hunger

Saxenda should be used alongside a reduced-calorie diet and increased physical activity for chronic weight management in adult patients with an initial body mass index, BMI of 30 (obese) or 27 or greater (overweight) in the presence of at least one other chronic health condition (e.g. high blood pressure, diabetes or high cholesterol).

Saxenda UK injections are not a miracle cure (though we wish it was).

Saxenda injection pens are a tool which should be used alongside a calorie deficit diet and a doctor approved exercise program.

This is why we'll send you an access code to the Liva Healthcare app when you buy from us, so you can track and monitor your health and lifestyle goals. You'll also have access to a Liva health coach to ask questions within the app.

The recommended Saxenda UK injection dosage when you start is 0.6mg once a day, which increases by 0.6mg each week (2).

A typical injection dosing schedule works like this:

• Week 1 - 0.6mg injection once daily for 7 days
• Week 2 - 1.2mg injection once daily for 7 days
• Week 3 - 1.8mg injection once daily for 7 days
• Week 4 - 2.4mg injection once daily for 7 days
• Week 5 - 3.0mg injection once daily ( this is the full dose and you will stay at this dose for as long as you need to.)

When you're starting out, a single Saxenda injection pen will last you 17 days.

If you buy a pack of 5 Saxenda injection pens, then they'll last you 44 days …

… so a 5 Saxenda injection pen pack will take you through to week 6.

Once you are at the optimum injection dosage (3mg/day), the 5 Saxenda injection pen pack should last you 30 days.

What needles do I use?

The Saxenda pen can be used with NovoFine 31G Tip, one of the thinnest and shortest needles available from Novo Nordisk. 31G Tip needles are single-use, disposable injection needles.

We will supply the pen with the needles and a yellow sharps box to dispose of used needles.

When the sharps bin is full, it should be returned to your nearest local Household Waste Recycling Centre where it will be disposed of properly. Only fill the bin up to where it say's "Do not fill above this line". You can find your local council here https://www.gov.uk/find-local-council

You must not put used needles or other sharps in any of your household waste bins.

Buy Saxenda Online View Saxenda Questions

1. Benefits of Saxenda [cited 12/08/21] Available at: https://www.saxenda.com/about-saxenda/benefits-of-saxenda.html

Cheapest Place to Buy Saxenda UK

Searching for the cheapest Saxenda UK pens is not the way to buy Saxenda. Saxenda is a prescription medication that requires a simple consultation.

You will need support and advice as you go through your weight loss journey, We provide you with this support.

Like all medicines, this medicine can cause side effects, although not everybody gets them.

Saxenda contains the active substance Liraglutide and helps aid adults with excess weight.

How To Purchase Saxenda Weight Loss Pens?

We are often told that to lose weight we simply have to eat less and move move but it’s actually much more complicated than that! Therefore, we can all benefit from a little help on our weight loss journey.

Saxenda is very effective tool to help lose weight and keep it off when used alongside healthy diet and regular exercise.

To purchase Saxenda UK weight loss products, you must complete the consultation to make sure it is safe and suitable for you.

WebMed Pharmacy specialises in treatments where patients may feel embarrassed or awkward talking to their GP or simply find it difficult to get an appointment or don’t want to take time off work. You can complete an online medical questionnaire in the comfort of your own home and if suitable can be prescribed by one of our own Doctors.

We offer a confidential, discreet next working day delivery of medicines, for sensitive or intimate conditions, within a one hour time slot to most postcodes in the UK.

We only supply UK sourced genuine medicines through our professional GPhC regulated pharmacy in discreet packaging with no reference to the pharmacy or medication.

You no longer do you have to wait around for days to see your GP or interrupt your busy daily routine.

Take a look at other articles about How does Saxenda Weight Loss Pen Work or How many Saxenda weight Loss Pens do I need?

What does the Saxenda pen look like?

The Saxenda pen looks like a pen when closed but is a prefilled self-injection that is used once daily.

You use the Saxenda weight loss pen as a gradually increasing the daily dose over the first 5 weeks.

If you are just starting to use Saxenda then a single pen should last 17 days and a pack of 5 pens should last 44 days.

Once you are on the full dose, a pack of 5 pens should last 30 days

If you want to know more about Saxenda and if it could work for you then call our pharmacy team 0161 491 1899. Your conversation will be in confidence and with discretion.

How long does Saxenda weight Loss pen last?

Saxenda is administered once daily.

You should follow a 5-week dose escalation to reach the fully effective 3-mg dose. The 5-week dose-escalation period can reduce the likelihood of gastrointestinal symptoms.

Saxenda Dose

The Saxenda starting dose is 0.6 mg subcutaneously, SC, per day for 1 week. You should increase the dose by 0.6 mg each week until the full maintenance dose of 3 mg is reached. By the start of the fifth week you should be on the maximum maintenance dose.

Dose Week 1 - 0.6 mg SC once daily x 7 days.

Dose Week 2 - 1.2 mg SC once daily x 7 days.

Dose Week 3 - 1.8 mg SC once daily x 7 days.

Dose Week 4 - 2.4 mg SC once daily x 7 days.

Dose Week 5 onwards - 3.0 mg SC once daily.

You should have lost at least 5% of your starting body weight by week 12 if you want to continue with Saxenda.

Saxenda is very effective tool to help lose weight and keep it off when used alongside a healthy diet and regular exercise.

• To purchase Saxenda UK weight loss products, you must complete the consultation to make sure it is safe and suitable for you.  

Webmed Pharmacy offer you support and advice, as you go through your weight loss journey.

Buy Saxenda Online 

Foods to avoid while on Saxenda?

There aren’t any specific foods to avoid while on Saxenda that you absolutely shouldn't eat. The Saxenda treatment plan is more focused on making it easier for you to stick to a calorie controlled diet.

Generally, you should cut down on the following foods to avoid while on Saxenda which are usually unhealthy:

High sugar foods, like;

• biscuits, cakes and chocolates
  
• Any fried food
  
• Excessive amounts of alcohol
  
• Any food high in saturated fats
  
• Fizzy type drinks that are high in sugar
  
• Avoid energy drinks or sweetened caffeinated drinks
  
• Large portions of food especially takeaway food where you don't know the calorie or nutrition content.

As there isn’t a specific diet plan designed for Saxenda, you should look to reducing your calorie intake and just as importantly, get some exercise like walking.

By reducing your appetite and making your food craving more manageable, Saxenda is designed to help you to eat fewer high-calorie foods and sustain your weight loss over time.


If you find it difficult to determine what to eat, you could go to the NHS web site and follow the NHS’s weight loss plan by downloading their free NHS Weight Loss Plan app https://www.nhs.uk/better-health/lose-weight/




There are many organisations you could join to give you support like Slimming World, Get Slim, weight watchers and healthier for life plant based diet program.




Before starting a weight loss plan or exercise plan, you should speak to your GP or health care provider first, to check the suitability in relation to your medical history or conditions.

How long does the Saxenda weight Loss pen last?

Saxenda weight loss pen is administered once daily.

How much Saxenda do I need and how long does it last?

You should follow a 5-week dose escalation to reach the fully effective 3-mg dose. The 5-week dose-escalation period can reduce the likelihood of gastrointestinal symptoms.

Saxenda UK Dose




The Saxenda UK starting dose is 0.6 mg subcutaneously, SC, per day for 1 week. You should increase the dose by 0.6 mg each week until the full maintenance dose of 3 mg is reached. By the start of the fifth week you should be on the maximum maintenance dose.

Week 1 - 0.6 mg SC once daily x 7 days.

Week 2 - 1.2 mg SC once daily x 7 days.

Week 3 - 1.8 mg SC once daily x 7 days.

Week 4 - 2.4 mg SC once daily x 7 days.

Week 5 onwards ı 3.0 mg SC once daily.

You should have lost at least 5% of your starting body weight by week 12 if you want to continue with Saxenda dose.

How To Purchase Saxenda Weight Loss Pens?


We all know that to lose weight we have to eat less and exercise more but we can all benefit from a little help on our weight loss journey. 

Saxenda is very effective tool to help lose weight and keep it off when used alongside healthy diet exercise.

Saxenda UK weight loss products are available by precription, to purchase Saxenda you must complete an online consultation, to make sure it is safe and suitable for you.

Buy Saxenda Online View Saxenda Questions

Wegovy vs Saxenda vs Ozempic

Those of us who are living with obesity could all do with a little help in the battle against it.

In the last few years Novo Nordisk have introduced some very effective tools to help win that battle.

These medications make you feel full and less hungry, which can help you to eat less and reduce your body weight. They can help you to not only lose weight but keep it off as well.

The first one to be introduced was Liraglutide which was originally developed as an anti-diabetic drug and is licensed for this purpose under the name Victoza.

When it was discovered that it could be a very effective weight loss aid it was developed for that purpose under the name Saxenda.

The same thing happened with Semaglutide, as it was developed as an anti-diabetic drug too and called Ozempic.

Some websites have already been selling Ozempic as a weight loss medication but it has only been approved by the Medicines and Healthcare products Regulatory Agency (MHRA), as an anti-diabetic medication and is not licenced for weight loss.

However, a new formulation of Semaglutide called Wegovy has been approved in the UK for weight loss and will soon be available.

What is Wegovy?

Wegovy™ is for adults with obesity (BMI ≥30) or overweight (excess weight) (BMI ≥27) who also have weight related medical problems, to help them lose weight and keep it off.

Problems like high blood pressure, high cholesterol and type 2 diabetes. Wegovy™ should be used with a reduced-calorie meal plan and increased physical activity.

How does Wegovy work?

Wegovy™ works by mimicking a hormone that targets areas of the brain involved in regulating appetite and food intake. It also delays gastric emptying which helps you to feel fuller for longer. This can help you eat less, which can lead to WEIGHT LOSS.

How do I take Wegovy?

Wegovy™ is the first and only prescription weight-management medicine taken once weekly. It’s taken on the same day each week, any time of day, with or without food.

Wegovy™ is available in 5 doses ranging from 0.25 mg to 2.4 mg, each of which is taken once a week for 4 weeks. Each dose comes in a different colour pen.

You should follow a 5-week dose escalation to reach the fully effective 2.4mg dose.

What is the difference between Wegovy and Saxenda ?

Both medications involve an escalating dosage schedule but Saxenda is injected on a daily basis while Wegovy is only injected on a weekly basis.

This is not the only difference however, as Wegovy produces much better weight loss and better cardiovascular outcomes.

In a 68-week medical study of 1,961 adults living with obesity or excess weight with a related medical problems:

ADULTS LOST ON AVERAGE 35 POUNDS (16KG) OR ABOUT 15% OF THEIR BODY WEIGHT!

What support do you offer?

We will not only supply you with medication to control your appetite but offer you lots of vital support to help you reach your weight loss goal and live your best life.

• We will provide 5 pillars of support to enable you to be successful on your weight loss journey and to give you the best possible outcome. These pillars will help you change to adopting healthy habits that will enable lifelong success.
• We will offer you lots of delicious healthy recipes with advice on eating out. There will be tips and advice on how to achieve restful sleep along with the recommended daily water consumption.
• There will be a fitness coach who will provide you with easy effective exercise routines that can be done in the comfort of your own home.
• Most importantly we will introduce you to our lifestyle coach who will offer you weekly interactive group coaching sessions to inspire you and help you overcome any obstacles that are holding you back from achieving your goal.

This will all be offered at no extra charge!

Email us at  team@webmedpharmacy.co.uk, to be notified when our new holistic weight management service will begin.

Wegovy is not available in the UK at them moment, but it will be soon. In the meantime we do have an alternative called Saxenda.

Buy Saxenda Online View Saxenda Questions

Medically reviewed by: Superintendent pharmacist Margaret Hudson BSc(Hons)MRPharmS 23/03/22

Saxenda UK, A New Weight Management Solution

Obesity is a growing problem in the UK.

A quarter of UK adults are obese and this proportion has risen due to the restrictions of lockdown.

Before the current pandemic, our increasingly sedentary lifestyles and readily available cheap unhealthy food, were resulting in us, as a nation, gaining weight. (1)

Previously, due to us being recommended to work from home, it has left us with ready access to the biscuit jar and unhealthy snacks, that has resulted in an exacerbated obesity problem.

It has been reported that, there is an increased risk in persons with obesity developing the Covid-19 disease. The obese tend to require hospitalisation and are more likely to be admitted to the Intensive Care Unit (ICU), to have invasive mechanical ventilation, suffering an increase in mortality. (6)

You can read our previous blog for more information about how Covid-19 affects those with obesity.

Most of us know that on a basic level, the key to losing weight is simply eating less and moving more, so on a daily basis, calories taken in, amount to less than calories you burn.

Many factors can stand in the way of this change in lifestyle, including time constraints and lack of motivation. In addition, several medical conditions such as Type II diabetes mellitus, pre-diabetes, polycystic ovarian syndrome (PCOS) and hypothyroidism, as well as certain medications, can make weight loss harder to achieve. That is why medical intervention may sometimes be needed. (1)

Until relatively recently, there was only one medication – orlistat – licensed to treat obesity in this country. Orlistat stops around a third of the fat in your diet being absorbed, helping to prevent weight gain.

However, unpleasant side effects related to this mode of action include oily, loose stools, flatulence, urgency to pass stools more frequently than is normal for you, and an oily rectal discharge. (1)

What is Saxenda and how does it work?

The best tool to be used in the battle against obesity is Saxenda, a brand of the medication liraglutide.

Liraglutide was originally developed as an anti-diabetic drug and is licensed for this purpose under the name Victoza, at a different strength to Saxenda.

Saxenda is available as a pre-filled pen for subcutaneous (under the skin) injection containing 18mg of liraglutide in 3ml of solution. (2)

Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist, meaning it acts at the receptor for GLP-1, an appetite-regulating substance naturally produced in the body. The way in which liraglutide interacts with the receptor is currently unclear. (2)

Saxenda is different from weight management products that you may have taken in the past.

Saxenda makes you feel full and less hungry, which can help you eat less and reduce your body weight.  It can help you to not only lose weight but keep it off as well.

We realise that losing weight is a complex issue and is not as simple as “eating less and moving more”. If only it were that simple!

That is why we have developed a holistic medicated solution to weight loss that will be available very soon.

We will offer 5 pillars of support to get you to your target weight and maintain it.

• We will have a fitness coach and a wellness coach.
• Our fitness coach has designed a series of simple easy exercises to do to boost your metabolism and our wellness coach will be hosting Saturday morning sessions where she will discuss all aspects of weight loss and be interested to hear how you are progressing and any topics you would like her to cover.
• We’ll have advice on how to achieve restful sleep and the recommended daily water consumption.
• There will be a Wellness App to help you when you feel stressed or anxious and this will be particularly helpful if, at moments like these, you are tempted to comfort eat.

With all the support that we will provide we aim to help to get you to your goal weight and stay there.

WATCH THIS SPACE!

Use the Saxenda pen at home or on the go

You can inject your dose in your stomach area (abdomen), upper leg (thigh), or upper arm. However, we would recommend the stomach area as you're less likely to feel it and you have a bigger area to vary where you inject.

Who can use  Saxenda?

Saxenda is licensed to treat obesity in people with a body mass index (BMI) of 30kg/m2 or higher, or those with a BMI of 27kg/m2 to 30kg/m2 who have one or more of a number of weight-linked health conditions including Type II diabetes mellitus, hyperlipidaemia (raised fat or cholesterol levels in the blood), high blood pressure and obstructive sleep apnoea.

It should be used in combination with a reduced-calorie diet and regular exercise. (2)

Children and young people under the age of 18 should not use Saxenda, as it is not yet known how the drug affects this age group. Furthermore, Saxenda should not be used by pregnant or breastfeeding women due to unknown effects on the foetus or baby. (3)

What is the dose for Saxenda?

When starting Saxenda, the initial dose is 0.6mg daily, injected into the abdomen, front of the thigh or upper arm, but not into a vein or muscle. The dose is increased on a weekly basis by a further 0.6mg until the daily dose is 3mg, the maximum recommended daily dose.

The reason for this gradual increase in dose is that gastrointestinal side effects, such as nausea, vomiting, diarrhoea and constipation are minimised.

These side-effects are very common, especially at the beginning of treatment, so lower doses at the start of treatment improve tolerability and make it more likely that the patient will continue treatment.

If Saxenda is still intolerable two weeks after stepping up to the next dose, treatment should be stopped. (2)

How long before Saxenda starts to work?

Patients using Saxenda can expect to have lost at least 5% of their starting weight once they have been on 3mg daily for twelve weeks, given they have also been consuming fewer calories and increasing exercise.

If this hasn’t been achieved, treatment with Saxenda should no longer be continued. (2)

What results have been seen with Saxenda?

Medical studies with more than 3,000 people taking Saxenda were conducted to understand the benefits and risks of Saxenda. The results from the study showed significant weight loss.

Along with a low-calorie meal plan and increased physical activity, some people lost nearly 2.5 times more weight with Saxenda versus placebo (17.3 lb vs 7 lb). Study participants had an average starting weight of 234 lb and an average BMI of 38. (3)

In a different 1-year study, most people who stayed on Saxenda kept the weight off. (3)

Can I use Saxenda alongside other medication?

If you use Victoza for diabetes you should not use Saxenda at the same time. This is because they both contain liraglutide, so using them together will lead to overdose.

Patients taking warfarin or other anticoagulants may need to have more frequent tests to monitor how long it takes their blood to clot. (4)

If you are on medication for diabetes then we will not be able to supply you with Saxenda as you need to be monitored by your healthcare provider. If your diabetes is managed by diet alone then we can supply it to you.

Where can I find Saxenda?

Saxenda is not usually prescribed by your GP and is only offered on the NHS through specialist multidisciplinary weight management (tier 3) services. Access to these services in variable throughout the UK and most people have to resort to buying it privately. (5)

It is available to purchase from Webmed Pharmacy following a simple online assessment by our Doctors - click here to see your options to buy Saxenda and find out if it is suitable for you.

What is Ozempic?

There have been recent posts in the media about some people who have lost a lot of weight using an unlicensed product for weight loss called Ozempic. (7)

The most important difference between Ozempic and Saxenda, is that Saxenda is licenced for use as a weight loss medication in the UK and Ozempic is not. Also, there is very little data available for the use of Ozempic in weight management.

Furthermore, it's unethical to routinely offer Ozempic in a weight management service but some websites and clinics will supply it routinely as they are only interested in making money and not concerned about your safety. You can read more about it here.

Buy Saxenda Online View Saxenda Questions

References

1.       NHS. Obesity – Overview [cited 1st March 2021]. Available at: https://www.nhs.uk/conditions/obesity/

2.       NICE. Obese, overweight with risk factors: liraglutide (Saxenda) – Product overview [cited 1st March 2021]. Available at: https://www.nice.org.uk/guidance/ta664

3.   Novo Nordisk. Saxenda [cited March 2021] https://www.saxenda.com/learn-about-saxenda/what-results-have-been-seen-with-saxenda.html

4.   emc. Saxenda 6 mg/mL solution for injection in pre-filled pen [cited 1st March 2021]. Available at: https://www.medicines.org.uk/emc/product/2313/pil

5.       NICE. Obese, overweight with risk factors: liraglutide (Saxenda) – Estimated impact for the NHS [cited 1st March 2021]

Available at: https://www.nice.org.uk/guidance/ta664

6.   World Obesity Organisation. [cited March 2021] https://www.worldobesity.org/resources/policy-dossiers/obesity-covid-19

7.    BBC NEWS. [cited March 2021]   Obesity: Appetite drug could mark 'new era' in tackling condition. Available at   https://www.bbc.co.uk/news/health-56011979

Author
Margaret Hudson
Superintendent pharmacist Margaret Hudson BSc(Hons) MRPharmS
Originally posted 27th December 2019, Saxenda: the newest recruit into the battle against obesity.

Updated: 1st March 2021

Updated 25th January 2022

Saxenda Weight Loss Injections

Saxenda weight loss injections, also known as ‘the skinny pen’ burst onto the U.K market back in 2017, with exciting results for people who need help with weight loss.

In one study of 3,731 people, 3 out of 5 achieved significant weight loss of 5% or more, and 1 in 3 achieved weight loss of 10% or more (1).

But how much does the weight loss pen, Saxenda weight loss injections, cost in the U.K? and is it worth it?

The truth is… it depends where you are in your weight loss journey right now.

If you need to lose a little weight and you’ve read about ‘the skinny pen’ then you may have been sucked into hype and need to be very, very careful. Saxenda weight loss injections are unlikely the best option for you if your Body Mass Index (BMI) is less than 27. Speak to your doctor.

If your BMI is over 27 and you have a weight related medical condition OR you’re living with obesity (have a BMI over 30) and have tried and failed at calorie controlled diets before… then this weight loss supporting injection may be the right next step for you (2).

How Saxenda works (and why we only recommend it if hunger is holding back your weight loss dreams).

Saxenda is the brand name for the active ingredient, Liraglutide. Liraglutide is an appetite suppressant that mimics the hormones in your brain that regulate hunger (3).

There is no guarantee that reducing hunger will delete extra weight, but reducing hunger pangs should help avoid the urge to overeat and to snacking in between meals.

Saxenda weight loss injections arn’t a miracle cure (though we wish it was).

It’s a tool which should be used alongside a calorie deficit diet and a doctor approved exercise program. This is why we’ll send you an access code to the Liva Healthcare app when you buy from us, so you can track and monitor your health and lifestyle goals.

You’ll also have access to a Liva health coach to ask questions within the app.

How much does Saxenda cost in the U.K?

To get the best results from Saxenda, you need to slowly increase your dose until you reach 3mg per day.

It’s easy to change the dose, you can see a simple dial mechanism at the top of the pen.

This means when you start, your pen will last much longer, because you are using less each time you inject than you will be when you are up to the full dose.

Here at our family owned pharmacy, we keep our prices as low as possible, and we help you with discounts to enable you to successfully continue on your weight loss journey..

So let’s look at a typical example.

The recommended dosage for Saxenda when you start is 0.6mg once a day, which increases by 0.6mg each week (2).

A typical dosing schedule works like this:

• Week 1: 0.6mg once daily for 7 days
• Week 2: 1.2mg once daily for 7 days
• Week 3: 1.8mg once daily for 7 days
• Week 4: 2.4mg once daily for 7 days
• Week 5: 3.0mg  once daily ← this is the full dose and you will stay at this dose for as long as you need to.

How does the dosage schedule affect the cost?

When you’re starting out, a single pen will last you 17 days.

If you buy a pack of 5 then they’ll last you 44 days…

...so a 5 pack will take you through to week 6.

Once you are at the optimum dosage (3mg/day), the 5 pen pack should last you 30 days.

In terms of investment… it depends how many pens you buy at a time. One pen works out at £75, but if you buy the 5 pen multipack, this is reduced to £60/pen (2).

How long do I need to take this for?

You’ll know pretty soon if this solution is working for you.

You should lose 5% of your starting body weight by week 12. If you have not achieved this using Saxenda, then you should stop the regime (always talk to your doctor or qualified pharmacist first). (2)

In terms of when you’ll stop, it depends on you and your progress. Some people stop when they hit their target weight, and some people continue to help them maintain their weight loss (1).

Here at Webmed Pharmacy, our lead pharmacist Margaret, is available during office hours to chat about your progress and answer any questions you have.

In fact, the manufacturer of Saxenda, Novo Nordisk, said this about us:

“Webmed's service is so supportive and ethical, it definitely stands out from the others”

Check out more about Saxenda

1. Benefits of Saxenda [cited 12/08/21] Available at: https://www.saxenda.com/about-saxenda/benefits-of-saxenda.html

2. Saxenda  [cited 12/08/21] Available at: https://webmedpharmacy.co.uk/buy/saxenda

3. How Saxenda Works  [cited 12/08/21] Available at:  https://www.saxenda.com/about-saxenda/how-it-works.html

Author: Gemma Boak

Medically reviewed by: Superintendent pharmacist Margaret Hudson BSc(Hons)MRPharmS 04/10/21

How Saxenda weight loss pens aid weight loss

Here we talk through appetite suppressant Saxenda and how long you can expect to wait before you see weight loss results.

Using Saxenda weight loss pens as part of a weight loss management plan that includes a calorie-controlled diet and exercise can help in the long term if you struggle to keep weight off. 

It works in the same way as the hormone glucagon-like-peptide (GLP-1) to regulate your appetite. This way you’ll feel fuller for longer and be able to resist snacking between meals or overeating - a contributing factor to obesity.[1] 

Saxenda dose – getting it right

Taking Saxenda can help you lose weight and keep it off, but this does require long-term commitment.

You begin by increasing the Saxenda dose by 0.6mg over the first four weeks so that from week five you’ll take the full 3mg dose (but no more). The pens are all pre-filled too, making it easier to use the correct dose.

For example:

Week 1: 0.6mg once daily for 7 days

Week 2: 1.2mg once daily for 7 days

Week 3: 1.8mg once daily for 7 days

Week 4: 2.4mg once daily for 7 days

Week 5 onwards: 3.0mg once daily

It’s important to follow this escalated Saxenda dosage to minimise any side effects and allow your body to adjust. The most common side effect is nausea affecting more than 1 out of 10 people, however, this should go away after a few days or weeks.[2]

Once you reach the full 3mg dose, you should keep going with this until your treatment ends.

Then, by week 16 you should have lost at least 5% of your total body weight – if you have, you can continue taking it. If not, it’s advised you discontinue as it may not be the right solution for you.[3]

Frustrated by slow progress?

Many people who take Saxenda give up before 16 weeks as they don’t see fast results, but it’s important to be aware that it takes time and your full commitment.[4]

Obesity is a complicated condition with over 100 different contributing factors of which many are out of your control.[5] It may be a frustrating and slow journey to embark on, but by keeping up your diet, exercise and Saxenda treatment you’ll see long-term benefits.

Why you should keep going (and when to stop)

Obesity can reduce your life expectancy by between 3 and 10 years, depending on the severity.[6] It can also cause serious complications like type 2 diabetes, asthma and high blood pressure.

But, by losing even a small amount of weight (for example 3%) you can significantly reduce the risk of these complications.[7]

Taking Saxenda for the full 16-week duration (or more) will increase your chances of losing weight and keeping it off…

In a study of people taking Saxenda, 3/5 achieved weight loss of 5% or more and 1/3 achieved more than 10% weight loss.[8]

However, it’s worth noting that you should stop treatment if you can’t stand the side effects as you increase the dose.

1. https://www.saxenda.com/about-saxenda/how-it-works.html
2. pil.2313.pdf (medicines.org.uk)
3. Saxenda® (liraglutide) dosing information | Novo Nordisk
4. https://www.nhs.uk/conditions/obesity/
5. https://www.obesityuk.org.uk/what-is-obesity
6. https://www.nhs.uk/conditions/obesity/
7. https://www.nhs.uk/conditions/obesity/
8. https://www.saxenda.com/about-saxenda/benefits-of-saxenda.html

Author: Gemma Boak

Medically reviewed by: Superintendent pharmacist Margaret Hudson BSc(Hons)MRPharmS 30/05/21

Saxenda side effects before and after?

Like all medicines, Saxenda can cause side effects, although not everybody gets them.

The most common adverse events experienced with Saxenda are gastrointestinal (GI) disorders.

The 4-week dose-escalation schedule was designed to minimise GI symptoms and most GI symptoms are mild to moderate and transient . (1)

What if I feel sick?

If you experience any nausea, it is advisable to eat smaller meals, stop eating when full and to make sure that you follow the dose escalation schedule.

What if I have diarrhoea or an upset stomach?

You may experience diarrhoea or constipation. In both cases it is very important to stay well hydrated. You can drink lots of fluids, such as water or squash – take small sips if you feel sick but do not have fruit juice or fizzy drinks as they can make diarrhoea worse.

If the diarrhoea persists then you can buy either oral rehydration sachets you mix with water to make a drink or medicine to stop diarrhoea for a few hours (like loperamide) from your local pharmacy. (2)

What if I am constipated?

To relieve constipation drink plenty of fluids and avoid alcohol, increase the fibre in your diet or add some wheat bran, oats or linseed to your diet. A daily walk or run can help you too as well as contributing to your weight loss! (3)

How do I prevent indigestion?

Indigestion can be remedied by cutting down on tea, coffee, cola or alcohol. Also, propping your head and shoulders up in bed can stop stomach acid coming up while you sleep.

Try to eat 3 to 4 hours before going to bed and avoid rich, spicy or fatty foods.

Avoid taking ibuprofen or aspirin as this can make indigestion worse. If you smoke, cutting down can help too.

If you are still suffering, then your local pharmacy can help with medicines that help reduce acid in your stomach, such as antacids and proton pump inhibitors (like Omeprazole 10mg). (4)

Some indigestion medicines are best taken after eating as their effects last longer. Check the information leaflet that comes with the medicines for more information.

What if I can’t sleep?

If you experience insomnia, then you can try changing your bedtime routine.

Try going to bed and waking up at the same time every day and only go to bed when you feel tired. Relax at least 1 hour before bed by taking a bath or reading a book. Make sure your bedroom is dark and quiet by using thick curtains, black out blinds, wearing an eye mask or ear plugs.

Exercising regularly during the day will help and make sure that you are comfortable in bed. (5)

What if I’m showing signs of low blood sugar (hypoglycaemia)?

Early signs of a low blood sugar level include:

• sweating
• feeling tired
• dizziness
• feeling hungry
• tingling lips
• feeling shaky or trembling
• a fast or pounding heartbeat (palpitations)
• becoming easily irritated, tearful, anxious or moody
• turning pale

If you experience any of the above then have a snack that contains a slow-release carbohydrate, such as a slice of bread or toast, a banana or a glass of cows' milk.

For a full range of potential side-effects visit https://www.medicines.org.uk/emc/files/pil.2313.pdf

However, most people only experience very mild side-effects that last only a short time as your body gets used to Saxenda and some people don’t have any at all.

Other Saxenda side effects

Common: may affect up to 1 in 10 people

Problems affecting the stomach and intestines, such as indigestion (dyspepsia), inflammation in the lining of the stomach (gastritis), stomach discomfort, upper stomach pain, heartburn, feeling bloated, wind (flatulence), belching and dry mouth

• Feeling weak or tired
• Changed sense of taste
• Dizziness
• Difficulty sleeping (insomnia). This usually occurs the first 3 months of treatment
• Gallstones
• Injection site reactions (such as bruising, pain, irritation, itching and rash)
• Low blood sugar (hypoglycaemia). - The warning signs of low blood sugar may come on suddenly and can include: cold sweat, cool pale skin, headache, fast heartbeat, feeling sick, feeling very hungry, changes in vision, feeling sleepy, feeling weak, being nervous, being anxious, confusion, difficulty concentrating and shaking (tremor). Your doctor will tell you how to treat low blood sugar and what to do if you notice these warning signs. increase of pancreatic enzymes, such as lipase and amylase which may lead to pancreatitis (Uncommon: may affect up to 1 in 100 people) .
• Loss of fluids (dehydration). This is more likely to occur at the start of treatment and may be due to being sick (vomiting), feeling sick (nausea) and diarrhoea
• Inflamed gall bladder
• Allergic reactions including skin rash
• Feeling generally unwell
• Faster pulse - Rare: may affect up to 1 in 1,000 people.
• Reduced kidney function - Acute kidney failure. Signs may include reduction in urine volume, metallic taste in mouth and easily bruising.

Worried about Saxenda side effects before and after?

To ensure Saxenda is suitable for you, we offer a free online consultation which is reviewed by our Doctors. Call Phone 0161 491 1899 if you have concerns or want to discuss Saxenda side effects with our pharmacy team.

1. Novo Nordisk Limited. Saxenda Summary of Product Characteristics [cited 2nd March 2021] https://www.medicines.org.uk/emc/product/2313#gref

1. NHS diarrhoea and vomiting [cited 2nd March 2021] https://www.nhs.uk/conditions/diarrhoea-and-vomiting/

1. NHS Constipation [cited 2nd March 2021] https://www.nhs.uk/conditions/constipation/

1. NHS Indigestion [cited 2nd March 2021] https://www.nhs.uk/conditions/indigestion/

1. NHS. Insomnia [cited 2nd March 2021] https://www.nhs.uk/conditions/insomnia/

1. NHS. Hypoglycaemia [cited 2nd March 2021] https://www.nhs.uk/conditions/low-blood-sugar-hypoglycaemia/

Author: Gemma Boak

Medically reviewed by: Superintendent pharmacist Margaret Hudson BSc(Hons)MRPharmS 02/03/21

What is Ozempic?

Recently, the media have been promoting a product called Ozempic and have quoted many success stories from people who have achieved dramatic weight loss by using it.

However, Ozempic is not licensed for weight loss and is actually licenced for use in the UK, to control type 2 diabetes.

Is there an alternative to Ozempic?

Yes, there is a very effective product called Saxenda, this is licenced in the UK for weight loss by the MHRA which is available now, to help make your weight loss journey much more successful.

Saxenda dramatically reduces your appetite and combined with a healthy diet and lifestyle can help you to achieve your weight loss goal.

What is the main difference between  Ozempic and Saxenda?

On reading the media articles it would appear, that the main difference between Saxenda and Ozempic, is that Saxenda is a daily injection and Ozempic is a weekly injection.

However, the most important difference between the two is, that Saxenda is licenced for use as weight loss medication in the UK and Ozempic is not.

Unfortunately, there are a few unscrupulous websites and weight loss clinics, that are selling Ozempic, putting profit before safety.

Is Ozempic safe and legal for weight loss?

Before a medicine can be widely used in the UK, it must first be granted a license.

Licences are only granted if strict safety and quality standards are met. In the UK, licences are granted by the Medicines and Healthcare products Regulatory Agency (MHRA). For more detail see the "MHRA Licence" section below.

In other words, Ozempic has not undergone clinical trials to see if it is effective and safe in treating weight loss, so does not have a product license in the UK for treating obesity.

Ozempic  has a product licence for controlling Type 2 diabetes, not for weight loss.

It contains the active substance Liraglutide which helps aid adults with excess weight ( BMI ≥28 ), who also have weight-related medical problems or those with obesity (BMI ≥30), to lose weight and keep the weight off. 

Will Ozempic be available in the future for weight loss?

In fact, Ozempic will never be granted a product licence for weight loss, as it is a brand name. It is the active ingredient in Ozempic called Semaglutide, that is currently undergoing clinical trials for the treatment of weight loss.

Semaglutide has now been granted a product licence for weight loss under the brand name of Wegovy and will be a different dosage to that used for diabetic control. We understand from the latest information that Wegovy will become available in the UK during the Spring of 2023.

In the meantime, it is safer to use the licenced product Saxenda.

Medically reviewed by
Superintendent pharmacist Margaret Hudson BSc(Hons) MRPharmS
16 February 2021 and updated 21 September 2022 and updated 21 November 2022