Contains Adapalene and Benzoyl Peroxide  that work together to treat acne.

It can be used on its own or in combination with the antibiotic Lymecycline for inflamed mild to moderate acne.

Do not use when pregnant or breastfeeding.

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What is Epiduo?

Epiduo is a gel that is used in the treatment of mild to moderate acne. It contains two active ingredients; benzoyl peroxide and adapalene. These ingredients are both used to treat acne and they work in different ways.

Benzoyl peroxide is an antimicrobial agent and works by killing bacteria on the skin as well as reducing whiteheads and blackheads.

Adapalene helps to reduce inflammation and black and white head formation on the outer layer of the skin.

How do I apply Epiduo?

Apply a thin layer of gel evenly over the acne affected areas only once daily at bedtime. Do not apply near or to the eyes, lips, nostrils or other sensitive areas. The gel should be applied to clean, dry skin and take care to wash your hands thoroughly before and after use.

Do not apply to broken skin.

How long does it take to see results?

As with all medicines applied to the skin in the treatment of acne, you may not see results for up to twelve weeks. It is important to be consistent in your application of this gel in order for it to work properly.

Is there anyone who can't use Epiduo?

Epiduo is not suitable for those with a hypersensitivity to any of the ingredients. Do not use in pregnancy or when breastfeeding. Avoid sunlight and UV lamps while using this medicine. Do not use other acne products containing retinoids or benzoyl peroxide while using this medicine or products that are irritating, drying or exfoliating to the skin.

Are there any side-effects?

Some people can experience stinging sensation, dryness, scaling and burning sensitivity when they first use this medicine. This presents worst during the first week of use and then tends to settle.

Are there any contra-indications or side-effects?

You should not use Epiduo if you think you might be pregnant, are pregnant or breastfeeding.

It is only safe to be used by women who are sexually active if they are using effective contraception. (Oral progestogen-only contraceptives not considered effective).

Medically reviewed by
4 April 2022

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