Tadalafil 10mg and 20mg

tadalafil (on-demand)

Buy tadalafil tablets online - lasts up to 36 hours

Tadalafil is a generic treatment for erectile dysfunction (ED) in men, available to buy online in 10mg and 20mg strengths.

Tadalafil is a much cheaper alternative to Cialis, the widely recognised treatment for ED. Referred to as ‘the weekend pill’, the medication works by increasing the blood flow to the penis, which helps to achieve and maintain an erection.

Those looking to buy Tadalafil online should note that in the UK, Tadalafil is only available with a prescription - at Webmed prescriptions are included FREE

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Pack size10mg20mg
4 tablets£20.00£20.00
8 tablets£30.00£30.00
12 tablets£40.00£40.00
16 tablets£50.00£50.00
24 tablets£70.00£70.00
32 tablets£90.00£90.00
64 tablets£140.00£140.00

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What is Tadalafil?

Tadalafil is the generic, unbranded version of Cialis, the widely recognised treatment for erectile dysfunction (ED). The medication works by increasing the blood flow to the penis, which helps to achieve and maintain an erection. As the patent for Cialis has now expired, Tadalafil is available for sale as a cheaper alternative for the treatment of ED. Those looking to buy Tadalafil online should note that in the UK, Tadalafil is only available with a prescription.

Treating Erectile Dysfunction (ED) with Tadalafil

Tadalafil is a recognised oral treatment for ED. The drug begins to take effect in a time window of about 30 minutes after it has been administered. Tadalafil can be effective for up to 36 hours, which is a much longer duration of time than alternative ED treatments such as Viagra. For this reason, Tadalafil has been referred to as 'the weekend pill', as you can take it on a Friday night and it's still effective on a Sunday morning. 

Tadalafil should not be viewed as a sexual stimulant on its own but able to produce a firm erection for satisfactory sexual intercourse when sexually aroused.

Product Information

Tadalafil vs Cialis

Medically, Tadalafil and Cialis work in the same way, as Tadalafil is the active ingredient in both treatments. Tadalafil and Cialis both work as PDE-5 inhibitors; giving the blood flow into the penis a boost and encouraging the achievement and maintenance of a harder erection. Like Cialis, Tadalafil is taken in advance of sexual intercourse, and can remain effective for up to 36 hours.

One of the main differences between generic, unbranded Tadalafil and the branded Cialis version, is the price point. Whereas Cialis is able to command a higher price thanks to the global brand recognition which it is has developed, Tadalafil can take advantage of its reduced overheads in terms of not being responsible for litany research and development including marketing and offer customers a lower price point.

Both Tadalafil and Cialis are available in doses that can be taken either on demand when anticipating sexual activity or every day in order to respond to any sexual stimulation spontaneously.

Thus, the only thing that separates them is price!


There are two forms of Tadalafil. Tadalafil 10mg and 20mg that are taken about 30mins before any anticipated sexual activity and Tadalafil Daily, for those who are more sexually active as it’s in your system continously and therefore you are able to respond to any sexual stimulation immediately.

The different manufacturers of Tadalafil use various bulking agents in their tablets and so they may appear differently.

The reason for the difference in appearance is due to the bulking agents or fillers of each brand of Tadalafil. There is only a very small amount of active ingredient, Tadalafil, in each tablet and to make the size more manageable for a patient, it is made bigger by the addition of these fillers. Patients can always check the Product Information Leaflet, PIL, supplied with each product for all ingredients, both active and inactive.

What dosage of Tadalafil should I take?

The recommended starting dose for Tadalafil is 10mg taken at least 30 minutes before sexual activity.  If this dose is effective but you experience side-effects, subsequent doses can be reduced to 5mg. If repeated trials of a 10mg dose prove ineffective, without side effects, the dose can be increased to 20mg.

No more than one Tadalafil tablet should be taken per day, and other ED treatments should not be taken within this time frame. Tadalafil tablets should only be taken to treat ED, not for 'recreational use' when not needed. They should be taken orally, with or without food, and swallowed whole.

The following warnings should be considered when taking Tadalafil:

  •  No more than one Tadalafil tablet should be taken per day 
  • Drinking alcohol at the same time as taking Tadalafil is not recommended, as alcohol is recognised as potentially decreasing the effect of the Tadalafil. This can depend on the amount of alcohol consumed, the strength of the Tadalafil dose and the quantities of food which have been consumed. Drinking alcohol with Tadalafil also increases your chances of suffering any side-effects.

  •  If after taking Tadalafil an erection is experienced for over four hours, a doctor should be consulted immediately. Without treatment for a prolonged erection, also known as priapism, serious damage to the penis can be caused.
  •  If a blurring or loss of vision is experienced after taking Tadalafil tablets, you should stop taking the medication and seek medical advice immediately.

If any of the following conditions apply to you, you should not take Tadalafil:

- You have suffered a stroke or heart attack in the previous six months
- You currently suffer from kidney or liver disease
- You currently suffer from irregular heart rhythm or heart disease problems
- You have low or uncontrolled high blood pressure
- You currently suffer from leukaemia or sickle cell anaemia
- You currently suffer from retinitis pigmentosa(an inherited disease of the eye)
- You currently suffer from haemophilia
- Your penis is physically deformed as in Peyronies disease
- You currently suffer from a stomach or duodenal ulcer

As Tadalafil is capable of lowering  blood pressure, the effect can be fatal if a nitrate drug (used to prevent or treat angina) is taken with it, for example  GTN spray, nitrate tablets, patches, gel or ointment or nicorandil. These are usually prescribed for heart conditions and you should consult your GP for other options.

Alpha blockers (used for an enlarged prostate) can’t be used in combination with Tadalafil, unlike Sildenafil due to it’s long duration of action.

What are the side effects of taking Tadalafil?

The side-effects of Tadalafil vary according to the individual.

The more common side effects of Tadalafil are facial flushing, indigestion, headaches and flu-like symptoms, muscle pain (myalgia), dizziness, nausea and blurred vision.


Can I buy Tadalafil online?

Yes, you can buy Tadalafil online but you should always buy it from an online pharmacy that is fully registered with the General Pharmaceutical Council, GPhC. This can be verified by checking for the GPhC logo on the website. The mandatory EU logo should also be present. These links should take you to the appropriate registers to verify the pharmacy's authenticity.

 Advantages of buying online from Webmed Pharmacy include being assured of genuine, effective medication with competitive pricing and fast discreet delivery, all from the comfort of your own home.

Do you need a prescription to buy Tadalafil?

Yes, you do need a prescription when buying this ED treatment. While Tadalafil is widely prescribed, it can also be unsuitable for some men. Before our GMC registered doctor prescribes Tadalafil for you, they will need to assess its suitability. This includes conducting checks related to your medical history and any other medications which you may be taking.

Our doctor assesses your suitability from the medical questionnaire that you are asked to complete before your prescription is issued, free of charge.  

 We then dispense your Tadalafil and supply it by courier, guaranteeing next working day delivery if ordered by 4pm.

What are the benefits of Tadalafil?

Tadalafil is sometimes known as the 'weekend pill', because it lasts for up to 36 hours - the longest lasting of any available ED medication. Other ED treatments typically stay in the system for four to six hours before the effect subsides. Tadalafil also begins to work quickly compared to other treatments, and only needs to be taken o 30 to 60minutes before sexual activity.

How long does it take for Tadalafil to work?

Tadalafil typically takes 30 to 60 minutes to take effect. This time may be affected by other factors including the amount of food consumed and whether alcohol has been drunk concurrently.

How long will my erection last on Tadalafil?

Tadalafil is proven to be effective for up to 36 hours. Erections when using Tadalafil will be achieved within this time frame when a man is sexually stimulated. Tadalafil won’t work unless you are sexually aroused.

How effective is Tadalafil in comparison to other ED medication?

The effect of Tadalafil typically lasts longer than the other ED treatments which are on the market - including Sildenafil, Levitra, Spedra and Viagra. It is proven to be able to provide an effective treatment for ED for up to 36 hours, compared to up to six hours for the other ED treatments. Tadalafil also begins to work more quickly than some of the other ED treatments - it can take effect in about 30 minutes.

Is Tadalafil better than Viagra?

Both Tadalafil and Viagra are recognised as effective treatments for ED. Which is the most effective can depend on the individual, although it should be noted that Tadalafil is typically effective for a longer time window (36 hours) than Viagra(4-6 hours), and can take as little as 30 minutes to take effect.

Also, Tadalafil is not affected by food unlike Viagra.

How much does Tadalafil cost?

Tadalafil prices can vary from pharmacy to pharmacy. Tadalafil will typically have a lower price point than Cialis, the branded form of the drug. Our customers can expect to pay as little as £2.19 per tablet. You will then receive a  discount on second and subsequent orders. This price includes your prescription and tracked next working day delivery.

Is Tadalafil the cheapest ED medication?

Tadalafil is an unbranded, generic version of Cialis, and for this reason can be bought for a lower price. Compared to other ED treatments, it is one of the cheapest. Prices vary from pharmacy to pharmacy, although sildenafil is typically the cheapest ED medication on the market.

How strong is Tadalafil?

There are two forms of Tadalafil.

Tadalafil 10mg and 20mg that are taken about 30mins before any anticipated sexual activity. They have the longest duration of action of all the ED medications as they last for 36 hours.

Tadalafil Daily, in doses of 2.5mg and 5mg, are better for those who are more sexually active as it’s in your system continuously and therefore you are able to respond to any sexual stimulation immediately.

Cialis comes in the same strengths but is much more expensive.

What strength of Tadalafil do I need?

The recommended starting dose for Tadalafil is 10mg. You can then move up to the higher 20mg dose if the 10mg is deemed to be ineffective and you haven't experienced any side-effects.

Individuals respond differently  to the same dose of Tadalafil and you may have to try the starting dose several times before you find it effective. 

What is the difference between Tadalafil and Cialis?

Tadalafil is the generic, unbranded version of Cialis. Tadalafil and Cialis are medically identical, containing the same active ingredient - which is Tadalafil. The main difference is that you can buy Tadalafil much more cheaply than Cialis.

Can you buy Tadalafil in the UK?

Tadalafil is a prescription only medication that can be supplied from registered and regulated online pharmacies like Webmed Pharmacy. Our GMC registered doctor supplies the prescription which the pharmacy then dispenses and delivers the next working day by tracked delivery as part of the standard service.

You can’t buy Tadalafil over the counter from a high street pharmacy in the UK.

Do I need to take Tadalafil every single day?

It depends on the dose of Tadalafil taken.

There are two different forms of Tadalafil.

Tadalafil 10mg and 20mg which can be taken about 30mins before it’s required. At Webmed Pharmacy we call this form, Tadalafil on Demand. The effects of both can last up to 36 hours and should only taken when sexually activity is anticipated.

We have another product called Tadalafil Daily that is taken every day. It comes in doses of 2.5mg and 5mg and is better for those who are more sexually active. You will be able to respond to any sexual stimulation spontaneously.

Can you buy Tadalafil over the counter?

No, Tadalafil can’t be bought over the counter from pharmacies in the UK. Tadalafil is a prescription only medicine (POM) and requires a prescription before it can be issued from a pharmacy.

Therefore, instead of asking your doctor for a private prescription, you can simply order online from Webmed Pharmacy where our GMC registered doctor issues your prescription and the medication is delivered to you the next working day.

Buying online is much more convenient and discreet than trying to get an appointment with your GP and possibly more competitively priced.

Can I take Tadalafil alongside other medications?

Whether you can take Tadalafil at the same time as your other medications will depend on which medications you are taking.

You are required to complete a short medical consultation questionnaire that asks for any medications that you are prescribed from your GP and will indicate the medications that can’t be taken alongside Tadalafil.

There are several medicines which should not be taken concurrently with Tadalafil. Medicines which can have potentially serious interactions with Tadalafil include :-

•           Any alpha-blocker medicines e.g. doxazosin (Cardura), alfuzosin (Xatral),      tamsulosin, terazosin, or Flomax, that you can buy in the pharmacy. (These medicines may be used to treat prostate problems or high blood pressure).

•           Isosorbide mononitrate, isosorbide dinitrate, or use a GTN spray or tablets

            for chest pain or use Rectogesic ointment?

•           Nicorandil (Ikorel), used to treat angina

•           Cimetidine, used to treat stomach or duodenal (peptic) ulcers

•           Theophylline, used to treat asthma

•           Antibiotics:- Clarithromycin, Erythromycin and Telithromycin

•           Anti-fungals such as itraconazole and ketoconazole

•           Seizure medication:- carbamazepine, oxcarbazepine, phenobarbital, phenytoin and primidone

•           Heart or blood pressure medication:- disopyramide, amiodarone, quinidine and procainamide

•           Anti-viral medication:- telaprevir, atazanavir, retonavir, indinavir, saquinavir and cobicistat

•           Recreational drugs:- amyl nitrate (poppers)

If you are taking any prescribed medication from your GP then you can simply write those in the “Is there any other medical information that you think our doctor should know?” section on the medical questionnaire. Then, our doctor will know whether the Tadalafil is safe for you to take.

Can I drink grapefruit juice when taking Tadalafil?

Grapefruit juice can affect your body's metabolism of Tadalafil.

The juice prevents the breakdown of Tadalafil in the body, allowing it’s greater absorption  from the gut into the bloodstream. This increases the risk of any unwanted side effects.

Therefore, it’s best not to drink grapefruit juice when taking Tadalafil. There are no such warnings attached to drinking orange or apple juice.

Can I drink alcohol while taking Tadalafil

There is no problem in having one or two units of alcohol (a small glass of wine or a small beer) with Tadalafil but any more than that will counteract the effects of the Tadalafil and you may be disappointed with your performance.

Also, Tadalafil can cause low blood pressure and dizziness which alcohol can also cause , increasing the likelihood of these side-effects.  Furthermore, taking both together may result in heart palpitations where the heart beats irregularly.

Therefore, drinking alcohol can not only be potentially dangerous but can ruin your sexual experience.

Can I get Tadalafil next day delivery when I buy online?

Yes. if an order is placed online before 4pm on a working day then it will be received by tracked delivery the next working day.  If an order is placed online before 4pm on a Friday then it can be delivered at the weekend for a small additional charge. Webmed Pharmacy delivers within an allocated one hour time slot, to most postcodes within the UK, which means you don't need to wait around all day for a delivery to arrive.

If you’re in a postcode area where we don’t use DPD your order will be delivered before 1pm the next working day by Royal Mail Special delivery.

How long does Tadalafil last for?

Tadalafil can be effective as an ED treatment for up to 36 hours. It should be noted that the effectiveness of Tadalafil will vary according to the individual. Tadalafil is considered the longest lasting ED treatment available in today's market.

How long does it take for Tadalafil to get out of your system?

After taking around 30 minutes to have an effect, Tadalafil can stay active in the system for as long as 36 hours. You should note that Tadalafil cannot produce an erection on its own and relies on sexual stimulation to do so.

Your overall health, any medications you’re taking, your diet, underlying health conditions, can all affect the amount of time Tadalafil takes to work in your body and how long it lasts.

Tadalafil has a half-life of 17.5 hours, meaning that every 17.5 hours after taking it, there's only half as much of the drug left. After 35 hours, a quarter and so on.

This means that Tadalafil is active for about 36 hours and you shouldn’t take another tablet within this time frame.

Is Tadalafil safe?

Tadalafil is an entirely safe ED treatment for many men, but if you suffer from certain medical conditions then Tadalafil may be an unsuitable treatment.

Also, it’s not suitable if you take certain medications.

Please see the Product Information section on this Tadalafil page for more information.

Download the Patient Information Leaflet

Medically reviewed by
4 February 2022

the same as Cialis but just much cheaper

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